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cyclosporine

Cyclosporine (Modified) capsules a generic to Atopica, are used for the treatment of atopic dermatitis in dogs, which is a non-contagious skin disease characterized by chronic inflammation of the skin.

Benefits:

How it works: Cyclosporine targets cells in the immune system that cause the allergic reaction in your pet. Dosage varies, and can taper off to fewer doses after several weeks. Consult with your veterinarian for specific treatment details.

Dosage & Administration: Give cyclosporine modified exactly as directed by your veterinarian. If you do not understand these directions, ask your veterinarian or pharmacist to explain them to you. Always give cyclosporine modified 2 hours before or 2 hours after a meal. Allow plenty of water for the pet to drink. Do not remove a capsule from the blister pack until required for use. When the capsule is removed from the blister pack there is a characteristic, noticeable smell which is normal. Your veterinarian may want your pet to have regularly scheduled blood tests during treatment to monitor effectiveness and side effects. Store cyclosporine modified at room temperature away from moisture and heat.

Directions:

Tip: Do not remove capsule from blister pack until required for use. When the capsule is removed from the blister pack there is a characteristic, noticeable smell which is normal.

Dosage:
Pet Weight Dosage
Dogs/Puppies:
(6 months and older)
Over 4 lbs Give 2.5mg per pound of body weight. The medication is usually given once a day to start until satisfactory improvement is seen, usually 4-8 weeks. The medication can then be given every other day until the clinical signs of atopic dermatitis are satisfactorily controlled, then the medication can be given every 3 or 4 days. Always give 1 hour before or 2 hours after a meal. Allow plenty of water for the pet to drink
Cats/Kittens:
(6 months and older)
Over 4 lbs Give 2.3-3.1mg per pound of body weight. The medication is usually given once a day to start until satisfactory improvement is seen, usually 4-8 weeks. The medication can then be given every other day until the clinical signs of atopic dermatitis are satisfactorily controlled, then the medication can be given every 3 or 4 days. Always give 1 hour before or 2 hours after a meal. Allow plenty of water for the pet to drink
Horses: X X
Storage: Store this product at room temperature. Some variation in the color of the powder may occur from batch to batch.

Ingredients:
Cyclosporine (Modified):
Active Ingredients Amount
Cyclosporine USP 25 mg
Other Ingredients: Dehydrated Alcohol 18.6%, dl-alpha-tocopherol, FD&C blue #2 aluminum lake, ferric oxide (yellow), gelatin, glycine, glycerol 85%, polyoxyl 40 hydrogenated castor oil, polyglycerol (3) oleate, polyglycerol (10) oleate, sorbitol solution, titanium dioxide.

Cyclosporine (Modified):
Active Ingredients Amount
Cyclosporine USP 50 mg
Other Ingredients: Dehydrated Alcohol 18.6%, dl-alpha-tocopherol, FD&C blue #2 aluminum lake, ferric oxide (yellow), gelatin, glycine, glycerol 85%, polyoxyl 40 hydrogenated castor oil, polyglycerol (3) oleate, polyglycerol (10) oleate, sorbitol solution, titanium dioxide.

Cyclosporine (Modified):
Active Ingredients Amount
Cyclosporine USP 100 mg
Other Ingredients: Dehydrated Alcohol 18.6%, dl-alpha-tocopherol, FD&C blue #2 aluminum lake, ferric oxide (yellow), gelatin, glycine, glycerol 85%, polyoxyl 40 hydrogenated castor oil, polyglycerol (3) oleate, polyglycerol (10) oleate, sorbitol solution, titanium dioxide.

What happens if I miss giving a dose: Give the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and give the next regularly scheduled dose. Do not give a double dose unless otherwise directed by your veterinarian.

What happens if I overdose the pet: Seek emergency veterinary medical treatment.

What should I avoid while giving Cyclosporine (Modified): The safe use in breeding, pregnant or lactating dogs has not been determined. Do not use cyclosporine modified in dogs with known allergy to the medication. The drug should not be used in dogs with kidney disease, stomach ulcers, and certain blood disorders. Prolonged use of cyclosporine modified can result in bacterial or fungal infection related to a decreased effect of the immune system.

Possible side effects of Cyclosporine (Modified): If any of the following serious side effects occur, stop giving cyclosporine modified and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing, swelling of the lips, tongue or face, and hives). Other less serious side effects may occur. Continue giving cyclosporine modified and talk to your veterinarian if your pet develops vomiting, soft stools or diarrhea, muscle cramps, muscle weakness, loss of appetite, and change of hair coat. Other side effects may occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

What other medications will affect Cyclosporine (Modified): There are many drug/drug interactions that occur when taking cyclosporine modified. Tell your veterinarian what medications your pet is currently using and any new products, including herbal remedies you may start to give. Drug/drug interactions could cause a decrease in effectiveness or an increase in side effects of either cyclosporine modified or the other medication being given. Examples of medications that may cause drug/drug interactions are; SMZ-TMP (Bactrim, Septra), gentamicin, etodolac (EtoGesic), piroxicam (Feldene), ketoconazole (Nizoral), cimetidine (Tagamet), ranitidine (Zantac), itraconazole (Sporanox), methylprednisolone (Medrol), erythromycin, Allopurinol (Zyloprim), metoclopramide (Reglan), prednisOLOne, digoxin (Lanoxin), any type of vaccination.

 

What should I discuss with my veterinarian before giving Cyclosporine (Modified): Tell your veterinarian if your pet has liver disease, kidney disease, cancer, high blood pressure, a viral, bacterial or fungal infection, or any other serious or chronic condition. Tell your veterinarian if your pet is pregnant or lactating, and if you plan to breed your pet.

Cautions: Consult your veterinarian about possible side effects or drug interactions.