Fluoxetine is an antidepressant belonging to a group of drugs called selective serotonin reuptake inhibitors (SSRI).
For: Cats and Dogs
How it works: Fluoxetine affects chemicals in the brain that can cause depression, panic, anxiety, or obsessive-compulsive behaviors.
Dosage & Administration: Give fluoxetine exactly as prescribed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. Do not give larger amounts or give it for longer than recommended by your veterinarian. Your veterinarian may occasionally change the dose to achieve the best result. It may take 3 to 4 weeks or longer before fluoxetine takes effect. Do not stop using fluoxetine without first consulting with your veterinarian. Unpleasant side effects can occur if the medication is stopped suddenly. Store fluoxetine at room temperature away from moisture and heat. Keep this medication away from children and other pets.
Tips: Do not give larger amounts or give for longer than recommended by your veterinarian. It may take 3 to 4 weeks or longer before Fluoxetine takes effect. Do not stop Fluoxetine without first consulting with your veterinarian.
What happens if I miss a dose: Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed the missed dose and give the next one as directed. Do not give a double dose of the medication.
What happens if I overdose the pet: Contact your veterinarian or veterinary emergency room. Symptoms of overdose may include nausea, vomiting, fever, sleepiness, rapid or uneven heartbeat, panting and irritability, confusion, fainting, seizures, and coma.
What should I avoid while using Fluoxetine: Avoid giving other medicines that can make the pet sleepy such as; cold or allergy medicine, pain medication, muscle relaxers, seizure medicine, or other medications for depression or anxiety. Tell your veterinarian if you give your pet any of these medications regularly.
Possible side effects of Fluoxetine: If any of the following serious side effects occur, stop giving fluoxetine and seek emergency veterinary medical attention; an allergic reaction (skin rash or hives, difficulty breathing, swelling of the face, lips, tongue, or throat). Call your veterinarian at once if your pet has any new or worsening symptoms such as mood or behavior changes, anxiety, panic attacks, trouble sleeping, irritability, agitation, hostility, aggression, restlessness, hyperactivity, or increased depression. Call your veterinarian at once if your pet has any serious side effects such as; seizures (convulsions); tremors, shivering, muscle stiffness or twitching; a red, blistering, peeling skin rash; problems with balance or coordination; or agitation, confusion, sweating, fast heartbeat. Less serious side effects may include drowsiness, dizziness, weakness, runny nose, sore throat, nausea, diarrhea, changes in appetite, weight changes, dry mouth. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
What other drugs will affect Fluoxetine: Talk to your veterinarian before giving your pet any medicine for pain, arthritis, fever, or swelling. This includes carprofen, piroxicam, etodolac, and others. Giving any of these medications with fluoxetine may cause the pet to bruise or bleed easily. Before giving fluoxetine, tell your veterinarian if your pet is being given digoxin, diazepam (Valium), phenytoin (Dilantin), warfarin (Coumadin), amitriptyline (Elavil), imipramine (Tofranil). Drugs other than those listed may also interact with fluoxetine. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines including herbal supplement.
What should I discuss with my veterinarian before using Fluoxetine: Do not give fluoxetine if your pet is using and MAO inhibitor such as Anipryl, selegiline, Preventic Collar, or Mitaban Dip. Serious and sometimes fatal reactions can occur when these medications are taken with fluoxetine. You must wait at least 14 days after stopping an MAO inhibitor before you can give fluoxetine. You must wait 5 weeks after stopping fluoxetine before you can give an MAOI. Tell your veterinarian if your pet is allergic to any medications of if your pet has liver disease, kidney disease, diabetes, or seizures. Fluoxetine should not be given to pregnant or lactating animals.
Cautions: Avoid giving other medicines that can make your pet sleepy (cold or allergy medicine, pain medication, muscle relaxants, seizure medicine, or other medications for depression or anxiety). Do not give Reconcile if your pet is using an MAO inhibitor such as Anipryl, selegiline, Preventic Collar, or Mitaban Dip. Side effects that may occur include rash, hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. If these or any other side effects occur, stop giving your pet Fluoxetine and contact your veterinarian.