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pilocarpine

Pilocarpine is a miotic agent (one that causes constriction of the pupil of the eye) used to treat canine primary glaucoma. It can also be used before or after eye surgery.

For: Dogs

Benefits:

How it works: Pilocarpine reduces pressure in the eye by increasing the amount of fluid that can drain from the eye.

Dosage & Administration: Use pilocarpine ophthalmic exactly as directed by your veterinarian. If you do not understand these directions, ask your veterinarian or pharmacist to explain them to you. Wash your hands before using the eye drops. Do not touch the dropper tip to any surface, including the skin or eye. The dropper tip is sterile. If it becomes contaminated, it could cause an infection in the eye. Do not use the eye drop that is discolored or has particles in it. Store pilocarpine ophthalmic at room temperature away from moisture and heat. Keep the bottle properly capped. Discard any unused medication on the expiration date.

Directions:

Tips: Wash your hands before using the eye drops. Do not touch the dropper tip to any surface, including skin or eye. The dropper surface is sterile. If it becomes contaminated, it could cause an infection of the eye.

Dosage:
Pet Weight Dosage
Dogs: All weights The dose used to treat primary glaucoma in dogs is 1 drop in the effected eye(s) 3 times a day. Do not use the eye drop if it is discolored or has particles in it
Cats: X X
Horses: X X
Storage: Store this product at room temperature, away from moisture and heat. Keep the bottle properly capped.

Ingredients:
Pilocarpine Ophthalmic Solution:
Ingredients (per mL): Amount
Pilocarpine Hydrochloride 20 mg

Preservatives Added
Benzalkonium Chloride 0.01%
Other Ingredients: Monobasic Sodium Phosphate, Hypromellose, Edetate Disodium, Dibasic Sodium Phosphate, Purified Water. Sodium Hydroxide and/or Hydrochloric Acid may be added to adjust pH.

What happens if I miss a dose: Apply the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not give a double dose of this medication.

What happens if I overdose the pet: Flush the pet¿s eye with water and seek emergency veterinary medical attention. Symptoms of a pilocarpine ophthalmic overdose may include vomiting, diarrhea, increased salivation, watering mouth, and tearing eyes.

What should I avoid while using Pilocarpine: Pilocarpine Ophthalmic may cause decreased vision in poor light. Do not touch the dropper tip to any surface, including your eyes and hands. The dropper tip is sterile. If it becomes contaminated, it could cause an infection in the pet¿s eye. Avoid other eye medications unless your veterinarian approves.

 

Possible side effects of Pilocarpine: Rarely, pilocarpine ophthalmic may cause retinal detachment. Retinal detachment can lead to blind spots, floaters in the visual field, and even blindness. Your veterinarian will want to check the pet's retina before use of this medication to determine if there is an increased risk of retinal detachment. If your pet experiences and of the following serious side effects, stop using this medication and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing, shortness of breath, swelling of the lips, face or tongue, or hives); diarrhea; watering mouth; urinary incontinence; muscle weakness; difficulty breathing; or an irregular heartbeat. Other less serious side effects may be more likely to occur. Continue applying pilocarpine ophthalmic and talk to your veterinarian if your pet has; burning, stinging, red, or tearing eyes; eyelid muscle twitches. Side effects other than those listed may also occur. Talk to your veterinarian about any side effect that seems unusual or that is especially bothersome to your pet.

What other drugs will affect Pilocarpine: Before using this medication, tell your veterinarian if your pet is using another eye medication, especially if it is a nonsteroidal anti-inflammatory drugs (NSAID) such as flurbiprofen (Ocufen), diclofenac (Voltaren), or ketorolac (Acular). Drugs other that those listed in this guide may also interact with pilocarpine ophthalmic. Talk to your veterinarian and pharmacist before using any prescription or over the counter medicines.

What should I discuss with my veterinarian before using Pilocarpine: Tell your veterinarian if your pet has ever had any type of retinal disease, retinal tear, or, if the pet has had cataract surgery. These conditions may increase the risk of retinal detachment. Tell your veterinarian if your pet has had heart failure, high or low blood pressure, asthma, stomach ulcer, epilepsy, hyperthyroid, blockage of the urinary tract, or difficulty urinating. Tell your veterinarian if your pet is pregnant or lactating or if you plan on breeding your pet.

 

Cautions: The dropper opening is sterile, so don’t touch it to any surface, including eyes or hands. If it becomes contaminated, it may cause an infection in the eye.